Notes :

Two-chain polypeptide hormone produced by the ?-cells of pancreatic islets. The ? and ? chains are joined by two interchain disulfide bonds. The ? chain contains an intrachain disulfide bond.

Insulin regulates the cellular uptake, utilization, and storage of glucose, amino acids, and fatty acids and inhibits the breakdown of glycogen, protein, and fat.

Serum-free medium supplements such as insulin are essential for long-term growth of commonly used mammalian cell lines. When insulin is absent from media, cell may exhibit disturbances in morphology and growth rate. r-Insulin Human (rHu) is identical in function and structure to the native human sequence. A hormone consisting of two polypeptide chains, rHu Insulin?s A-chain (21 amino acids) and B-chain (30 amino acids) are covalently linked by disulfide bonds between cysteine residues. This genetically engineered human insulin is a full sequence molecule produced by recombinant DNA technology in baker?s yeast.

Animal Component Free.

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